Jun 13, 2026  
**DRAFT**2026-2027 Undergraduate Catalog 
    
**DRAFT**2026-2027 Undergraduate Catalog

Medical Laboratory Science (B.S.)


82-92 Major Hours, 120 Degree Hours


MLS 439-449 (Senior Clinical Year) 29-38 hours from the courses below:


*Course requirements are developed in conjunction with the affiliated clinical sites to meet the NAACLS accreditation standards. These requirements may be subject to change and vary by site.

Double Major Options/Course Double Count


a The combination of BIOC 430 & 431 meets the MLS BIOC 310/L requirement and may count for both the MLS & Biochemistry or the MLS & Medical Biology double majors.

b Denotes courses that may count for both the MLS & Chemistry, or MLS & Biochemistry, or MLS & Medical Biology, or MLS & Physiology, Cell, & Molecular Biology double majors.

c Four credit hours of upper-level Chemistry courses may count for both the MLS & Chemistry, or MLS & Biochemistry, or MLS & Medical Biology, or MLS & Physiology, Cell, & Molecular Biology double majors.

d BIOL 420 & 420L meets the MLS 239 & 239L requirement for MLS & Medical Biology, or MLS & Physiology, Cell, & Molecular Biology double majors.

e The combination of BIOL 471 & 475 meets the MLS 325 requirement for MLS & Medical Biology, or MLS & Physiology, Cell, & Molecular Biology double majors.

f The combination of BIOL 428/L and ANAT 411 or BIOL 428/L and BIOL 481/L may meet the anatomy/physiology requirements for MLS & Medical Biology, or MLS & Physiology, Cell, & Molecular Biology double majors.

g Denotes courses that may count for both the MLS & Medical Biology, or MLS & Physiology, Cell, & Molecular Biology double majors.

Suggested Courses For All MLS Majors


Declaration of Medical Laboratory Science Major


Students may be eligible to declare the Medical Laboratory Science major after successful completion of 12 credits with confirmation of good academic standing defined as a cumulative GPA at or above 2.0  per SDBOR policy 2.8.1.C(4).  
 
Completion of the declaration of MLS major does not guarantee placement for clinical internship. There will be an additional external application process. Each clinical site has their own minimum requirements and application process. Students may apply to any number of USD’s clinical affiliates. Details of affiliates’ requirements can be found on their respective websites which can be accessed via USD MLS website.   

Four-Year Program Guides and Costs


USD encourages students to take 15 credits per semester or 30 credits within the year in order to graduate in 4 years. To help students complete their academic degree program in four years, we provide a sample academic plan. Please work with your academic advisor to confirm your plan. 

  • Medical Laboratory Science, B.S. 4-year plan guide

Location Matters in Medical Laboratory Sciences


USD’s Bachelor of Science in Medical Laboratory Sciences prepares graduates to take the American Society for Clinical Pathology Board of Certification (ASCP-BOC) exam. State licensure or certification is not required to work as a Medical Laboratory Scientist in South Dakota, but it may be required to work in other states. If you are planning to apply for licensure/certification in a state other than South Dakota after completion of your program, please review that state and your program on USD’s Licensure-Track Programs webpage.

Additionally, this program is authorized to offer supervised field study placements (internship, externship, clinical, rotation, practicum, independent study, study away, etc.) in South Dakota. Please be aware that there may be some restrictions on your ability to engage in supervised field study outside of South Dakota. If you have questions regarding supervised field study, please contact a program representative or visit USD’s State Authorization page.